Risk Stratification of Stress Fractures and Prediction of Return-to-Duty
Technical Report,15 Nov 2015,14 Nov 2016
Massachusetts General Hospital Boston United States
Pagination or Media Count:
This second annual report reviews progress towards completing each of our three study tasks. Major accomplishments include IRB renewal for all study protocols, hiring and training of new staff at MGH, as well as the completing subject enrollment for Task 1 and continuing enrollment for Task 3. In study Task 1 we aim to determine the sex- and race-ethnicity-specific bone traits that may contribute to stress fracture risk in military recruits. We are ahead of schedule by increasing our study size and completing study enrollment, with 185 subjects enrolled n 50 White women, 50 White men, 51 Black women, 34 Black men. Data analysis and manuscript preparation are underway. In study Task 2 we aim to quantify changes in bone structure and bone metabolism in recruits before and after Basic Combat Training BCT. Enrollment and data collection are complete, and data analysis is ongoing. Finally, for study Task 3 we aim to characterize recovery and predict bone-healing trajectories and develop return-to-duty guidelines. We hypothesize that changes in bone health during recovery from stress-fracture injury can be quantified and used to develop evidence-based RTD. Enrollment is underway, with 13 women with recent stress fracture enrolled.
- Anatomy and Physiology
- Medicine and Medical Research