A New Tool for Local Manipulation of Neuronal Micro-Circuitry with Ions and Force
Technical Report,30 Jul 2015,30 Sep 2016
Regents of the University of California Santa Barbara United States
Pagination or Media Count:
Our goal is to compute the complete functional connectivity map of a living neuronal network spontaneously assembled in culture and determine the utility of its information content as a synthetic memory trace. To date no functional connectivity map exists for living neurons at the resolution proposed here. In fact, a quantitative model of the microcircuitry at the level of the single synapse remains inaccessible with current technology. We will develop a deep learning module for diagnosing MEA patterns and establish a complete connectivity map for hippocampal cultured neurons.
- Medicine and Medical Research