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Automated Comprehensive Evaluation of mTBI Visual Dysfunction

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Technical Report,15 Sep 2015,14 Sep 2016

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Geneva Foundation Tacoma United States

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The purpose of this study is to validate the Neuro-Ophthalmic Device NODe test battery that provides the highest sensitivity and specificity for the detection of oculomotor and high order visual processing dysfunctions on a large population of Warfighters with acute mTBI as compared to healthy age-matched controls. This study also will demonstrate that a comprehensive combination of biomarkers will be more specific to mTBI than any one test alone and that the tests within the NODe test battery can serve as objective biomarkers for acute mTBI. Two hundred acute mTBI 72 hrs post injury and 200 age-matched non-TBI controlsmilitary personnel will be recruited from the patient population at Womack Army Medical Center WAMC. The central hypothesis is that a NODe test panel evaluating visual function can detect neurological and ophthalmological changes induced by acute mTBI compared to age-matched controls.

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