Antimicrobial Silk Ocular Drug Delivery Implant for Chronic Posterior Segment Diseases
Technical Report,15 May 2015,14 May 2016
Tufts University Medford United States
Pagination or Media Count:
An intreocular insert based on fibroin was designed and optimized. The insert contains a hollow channel that was preloaded with the anti-VEGF antibody bevacizumab. The device was covalently coated with the antibacterial polymer HMPE1 to protect against biofilm formation and the transmission of harmful bacterial to the interior of the ocular chamber.
- Medicine and Medical Research