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Frontoparietal priority maps as biomarkers for mTBI

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Technical Report,30 Sep 2015,29 Sep 2016

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University of Minnesota Minneapolis United States

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This project involves a series of behavioral and magnetic resonance imaging MRI experiments that will determine the degree to which difficulties with visual attention, saccade targeting and motion perception associated with mild traumatic brain injury mTBI can be attributed to damaged cortical brain networks serving attention and eye movement planning. The hypothesis being tested is that spatial attention and eye movement deficits associated with mTBI result from disruption of the gray matter andor the white matter in cortical networks that control attention allocation and eye movements. A combination of functional MRI and diffusion-weighted imaging will allow us to measure 1 integrity in cortical networks in frontal and parietal brain regions responsible for attention allocation and eye-movement planning, 2 integrity in the white matter carries outputs from these regions to the sub-cortical nuclei that control eye movements, and 3 correlation between these biomarkers and behavioral measures of visual performance in veterans who have and have not experienced mTBI. No results are available at the time of writing preliminary data analysis is underway.

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