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Supplemental Perioperative Oxygen to Reduce Surgical Site Infection After High Energy Fracture Surgery
Technical Report,30 Sep 2015,29 Sep 2016
University of Maryland, Baltimore Baltimore United States
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Our study is a multi-center prospective randomized treatment trial investigating if supplemental perioperative oxygen use will reduce surgical site infection after surgery on fractures with a high risk of infection. The study utilizes the DOD-funded Major Extremity Research Consortium METRC. The study population is calcaneus, pilon, and tibial plateau fractures. During the first year we created a protocol committee, designed and approved the protocol and CRFs, obtained IRB approval. We have enrolled 624 patients to date at 20 centers. Follow up rate has been strong with 88 at 12 months. The study will likely receive a major enrollment boost when the competing METRC VANCO study finishes enrollment this year and high volume sites switch to OXYGEN thus allowing completion of the OXYGEN study in a reasonable time.
APPROVED FOR PUBLIC RELEASE