Identification of Novel Drug Targets and Lead Compounds for Advanced Prostate Cancer through Genomic and Cheminformatic Analyses
Technical Report,01 Aug 2014,31 Jul 2016
University of British Columbia Vancouver Canada
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Prostate cancer PCa is one of the most common cancers for males in the United States and Canada. When PCa is diagnosed early, it can be treated by surgery or radiation. However, inabout 30 of cases when PCa recurs or metastasizes, the disease is managed primarily by hormone therapy. Unfortunately, the effectiveness of this therapy is temporary due to emerging resistance mechanisms.