Accession Number:

AD1024148

Title:

Genetic Modifiers of Ovarian Cancer

Descriptive Note:

Technical Report,15 May 2010,14 May 2014

Corporate Author:

Mayo Clinic Rochester United States

Personal Author(s):

Report Date:

2014-08-01

Pagination or Media Count:

150.0

Abstract:

Individuals with germline mutations in BRCA1 have an elevated but incomplete risk of developing ovarian cancer suggesting the presence of genetic modifiers of ovarian cancer in this population. A genome wide association studyGWAS for ovarian cancer in BRCA1 mutation carriers has identified several novel modifiers of ovarian cancer risk for BRCA1 mutation carriers that can be used for individualized ovarian cancer risk assessment.

Subject Categories:

  • Genetic Engineering and Molecular Biology
  • Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE