Accession Number:

AD1023945

Title:

Beneficial and Deleterious Bacterial - Host Interactions in Chronic Wound Pathophysiology

Descriptive Note:

Journal Article

Corporate Author:

University of Texas at Austin Austin United States

Personal Author(s):

• Watters,Chase
• Yuan,Tony T.
• Rumbaugh,Kendra P.

Report Date:

2015-04-02

Pagination or Media Count:

13.0

Abstract:

Chronic wounds represent a major health and financial burden. Although incredible advancements in wound management have been made in the last decade, the incidences of chronic wounds continue to increase due to a rise in biofilm-associated infections. The presence of biofilm causes chronic inflammation, leading to impaired healing rates and host mortality. This review describes the deleterious bacterialhost interactions, as well as the beneficial role of pH and probiotics in chronic wound infections.

Descriptors:

• wounds and injuries
• wound infections
• inflammation
• BIOMATERIALS
• staphylococcal infections
• bacterial infections

Subject Categories:

• Medicine and Medical Research
• Weapons Effects (Biological)

Distribution Statement:

APPROVED FOR PUBLIC RELEASE