Pilot Comparisons of Temporary Open Revascularization Using Stent Grafts vs. Standard Shunts in a Sheep (Ovis aries) Model
DAVID GRANT USAF MEDICAL CENTER TRAVIS AFB CA TRAVIS AFB United States
Pagination or Media Count:
Objectives Pilot study and development of an experimental model to test and compare the performance of endovascular stent-graft as an arterial shunt. Methods Developed a model of vascular shunting in an Ovine model. Develop methods of observing and measuring the performance of these vascular shunts. Results Exposure and placement of vascular stent-grafts and shunts into the common carotid artery was feasible. Stent-graft and shunt performance could be observed through pressure monitoring, duplex and contrast angiography. Consistently observed low resistance flow patterns, the highly mobile nature of the area and early graft failure during model development raised the question of the appropriateness of this anatomic region for testing of stent-graftshunts to be used to treat peripheral vascular injury. Conclusion Study of endovascular stent-grafts for use as a vascular shunt is feasible. Graft performance may be measured through pressure monitoring, duplex, and angiography. Use in the carotid artery may confound results and limit relevance to proposed use in the management of peripheral vascular injury.
- Medicine and Medical Research