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Evaluation of 10 Jet Fuels in the Salmonella-Escherichia coli Mutagenicity Assay

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Technical Report,01 Oct 2013,30 Apr 2014

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Naval Medical Research Unit Dayton Wright-Patterson Air Force Base

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The focus of this study was to evaluate the toxicity of ten jet fuels of interest to the United States Department of Defense. Specifically, this study aimed to determine the potential of the jet fuels to induce DNA damage that may lead to genetic mutations. All of the jet fuels tested were considered to be negative for mutagenicity in the bacterial reverse mutation assay using Salmonella and E. coli strains. Based on the parameters used in this in vitro study, Citgo JP8 POSF 4658, Valero 25 Aromatic JP8 POSF 8457, KiOR Hydrotreated KeroseneBio-Kerosene POSF 10327, ARA ReadiJet POSF 10328, Amyris Farnesane POSF 10329, Virent HDO-SK POSF 10330, TS-1 Specification number 10227-86, Gevo 7695 with JP8 additives POSF 7699, Gevo 10262 with JP8 additives POSF 10263, and Swedish Biofuel 7633 with JP8 additives POSF 8452 are considered to be nonmutagenic.

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