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Personal Protective Equipment In Animal Research - Back To The Basics (A review paper)

Descriptive Note:

Journal Article

Corporate Author:

ArmyMedical Research Institute of Infectious Diseases Frederick United States

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The occupational health and safety program OHSP is an integral component of an animal care and use program. Exposures of animal care and research personnel to allergens and physical, chemical, radiological, and biological hazards can occur in the conduct of various tasks, thus it is important to mitigate the risk of such exposures. This is especially true in infectious disease and biocontainment research. One aspect of the program is the provision of personal protective equipment PPE. Commercially available PPE should be carefully evaluated based on its material composition and performance per manufacturer data. To help institutions and end users by providing them guidance on choosing appropriate PPE, this review paper discusses the regulatory framework, device standards, and materials engineering for various PPE, including gloves, shoe covers, head caps, gowns, aprons, masks, hearing and eye protection devices, and respirators. Ultimately, the choice of appropriate PPE is based upon the risk assessment, which should include consideration for personnel comfort, proper device fitting, and the containment level for the hazard used. The use of animals in research comes with the innate risk of accidental exposure of personnel to various hazards. Animals produce allergens from body secretions and products including dander, urine and saliva. Meanwhile, chemicals like chlorine-based solutions and quaternary ammonium compounds are commonly used for environmental sanitation and disinfection. Others like bromodeoxyuridine and tricaine methanesulfonate, and radioactive substances such as bio imaging tracers are used for animal experimentation.

Subject Categories:

  • Protective Equipment

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