Accession Number:

AD1022095

Title:

An Unconventional Approach To Reducing Retinal Degeneration After Traumatic Ocular Injury

Descriptive Note:

Technical Report,01 Jul 2015,30 Jun 2016

Corporate Author:

SUNY Downstate Medical Center Brooklyn United States

Personal Author(s):

Report Date:

2016-07-01

Pagination or Media Count:

11.0

Abstract:

This project seeks to image abnormal retinal pericyte vasospasms after ocular trauma in mice, and their relationship to retinal macrophage activity, and oral administration of L-Arginine. In the first year we overcame significant technical difficulties with in vivo fluorescent labeling of retinal pericytes, using both fiber-optic confocal and multiphoton microscopic imaging techniques, and we successfully established the imaging protocol for in vivo retinal pericyte imaging with simultaneous measurement of microspasms in retinal capillary beds.

Subject Categories:

Distribution Statement:

APPROVED FOR PUBLIC RELEASE