Can Post mTBI Neurological Soft Signs Predict Postconcussive and PTSD Symptoms : A Pilot Study
Technical Report,20 May 2011,19 Nov 2013
The Massachusetts General Hospital Boston United States
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Neurological soft signs NSS are subtle indicators of brain dysfunction. NSS have been found to be elevated in a variety of mental disorders, including post-traumatic stress disorder PTSD, but they have scarcely been studied in TBI. The present study measured NSS in the acute aftermath of a mTBI and evaluated their ability to predict subsequent postconcussive symptoms. We have finished all study recruitment, enrollment, and data analysis. We screened 99 subjects via the Massachusetts General Hospital Emergency Department leading to 21 viable subjects that were enrolled, three of whom were subsequently excluded for not meeting eligibility criteria. One additional subject was lost to follow-up after completion of the first visit. The remaining 17 enrolled subjects have successfully completed the full three-month protocol. The video-recorded data for all subjects was encrypted and analyzed by our off site consultant, Dr. Gurvits, the originator of the NSS battery incurrent use. A manuscript has been prepared and awaits submission.