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The Role of Novel Substituted Diindolyl Methane Analogues in the Treatment of Triple-Negative and ErbB2-Positive Breast Cancer

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Technical Report,01 May 2015,30 Apr 2016

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Florida A and M University Tallahassee United States

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The mission of the proposed HBCUMI Breast Cancer Partnership Training Award at Florida A and M University FAMU is to develop a rich intellectual environment that will promote and strengthen the research capabilities of FAMU investigators in the area of breast cancer research. The objectives this proposal are 1 to provide mentorship and training to FAMU researchers in breast cancer research area to enhance the research expertise and competitive ability 2 to train FAMU investigators through a well defined research project investigating the anticancer potential of C-DIM analogs in treatment of breast cancer 3 to develop FAMU investigators grantsmanship skills by submitting extramural grants for independent funding and 4 to create awareness among FAMU researchers and African American Community about breast cancer biology and therapy. The outcome of this proposal will lead to novel oral therapeutic strategies for treatment of triple negative breast cancer TNBC and ErbB2-positive breast cancer EPBC and also result in publications in highly ranked journals. This approach will result in establishment of a successful and independently funded breast cancer research program at FAMU.

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