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Use of Isolated Mitochondria and Pulmonary Artery Endothelial Cell Systems in Studies of Oxygen Utilization and the Effects of Hemoglobin-Based Oxygen Carriers
Uniformed Services University Of The Health Sciences Bethesda United States
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Hemoglobin-based oxygen carriers HBOCs with various oxygen affinities are currently being evaluated for clinical use. We tested whether HBOCs with high vs. low oxygen affinities can affect molecular oxygen on and offloading, using isolated mitochondria and Bovine Pulmonary Artery Endothelial CellsBPAECs as model systems.
APPROVED FOR PUBLIC RELEASE