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Accession Number:
AD1013538
Title:
Optimization of Soft Tissue Management, Spacer Design, and Grafting Strategies for Large Segmental Bone Defects using the Chronic Caprine Tibial Defect Model
Descriptive Note:
Technical Report,30 Sep 2014,29 Sep 2015
Corporate Author:
University of Minnesota Minneapolis United States
Report Date:
2015-10-01
Pagination or Media Count:
17.0
Abstract:
This proposal addresses the treatment of segmental bone defects and methods that can be used to manipulate the Masquelet induced membrane IM to create a graft bed that optimizes bone regeneration. The results showed that scraping the inner surface of the induced membrane provided a highly desirable environment that promoted more bone regeneration by exposing the autograft placed in the defect site to fresh blood and competing non-osteogenic cells.
Distribution Statement:
APPROVED FOR PUBLIC RELEASE