The Comparative Efficacy of 0.12% Chlorhexidine and Amoxicillin to Reduce the Incidence and Magnitude of Bacteremia During Third Molar Extractions: A Prospective, Blind, Randomized Clinical Trial
Uniformed Services University Of The Health Sciences Bethesda United States
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Although the evidence is purely circumstantial, it has been postulated that dental treatment procedures cause a transient bacteremia which may predispose patients with cardiac anomalies to IE and patients with a prosthetic joint to late prosthetic joint infections if not treated with antibiotic prophylaxis however, there is minimal evidence-based data to support such a hypothesis. The purpose of this study is to determine the effect of a pre-procedure rinse of 0.12 chlorhexidine on the incidence and magnitude of bacteremia compared to the AHA recommended antibiotic prophylaxis guideline of 2g amoxicillin during third molar extractions.