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The Comparative Efficacy of 0.12% Chlorhexidine and Amoxicillin to Reduce the Incidence and Magnitude of Bacteremia During Third Molar Extractions: A Prospective, Blind, Randomized Clinical Trial
Uniformed Services University Of The Health Sciences Bethesda United States
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Although the evidence is purely circumstantial, it has been postulated that dental treatment procedures cause a transient bacteremia which may predispose patients with cardiac anomalies to IE and patients with a prosthetic joint to late prosthetic joint infections if not treated with antibiotic prophylaxis however, there is minimal evidence-based data to support such a hypothesis. The purpose of this study is to determine the effect of a pre-procedure rinse of 0.12 chlorhexidine on the incidence and magnitude of bacteremia compared to the AHA recommended antibiotic prophylaxis guideline of 2g amoxicillin during third molar extractions.
APPROVED FOR PUBLIC RELEASE