Periodontal Regeneration Of 1-, 2-, and 3-Walled Intrabony Defects Using Accell Connexus (registered trademark) Versus Demineralized Freeze-Dried Bone Allograft: A Randomized Parallel Arm Clinical Control Trial
Uniformed Services University Of The Health Sciences Bethesda United States
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Combination therapy, in guided tissue regeneration GTR, is often used in the treatment of intrabony defects. Particulate demineralized freeze- dried bone allograft DFDBA is a bone grafting materials used successfully in GTR on humans for almost 30 years. A newer form of DFDBA, Accell Connexus Accell, has been FDA approved for use in periodontal regeneration which is the growth of new bone, cementum and periodontal ligament on a previously diseased tooth root surface. Accell Connexus contains 5-7 times more bone morphogenic proteins BMP than the traditional particulate DFDBA. This increase in BMP is thought to increase the potential of periodontal regeneration.