Accession Number:



Physical Activity as a Trigger of Ambulatory Myocardial Ischemia in Patients with Coronary Artery Disease: Assessment Using Automated Activity Monitors

Descriptive Note:

Technical Report

Corporate Author:

Uniformed Services University Of The Health Sciences Bethesda United States

Personal Author(s):

Report Date:


Pagination or Media Count:



This study used automated physical activity monitors to objectively examine the relationship between heightened physical activity levels and the occurrence of daily life ischemia in patients with coronary artery disease CAD. A total of S4 ischemic episodes were recorded in 21 CAD patients 2.6 - 2.3 episodesperson during 883 hours of continuous ECG and activity monitoring. The results of this study indicated that episodes of activity-induced ischemia occurred throughout the day, but tended to peak in the early morning hours due to dramatic shifts in activity and heart rate concomitant to the initiation of morning activities upon arising. In general, gradual increases in physical activity and heart rate were observed during the hour before the onset of ischemia. The findings of this study provide objective corroboration of previous self-report investigations of activity-induced ambulatory ischemia and highlight the potency of increased myocardial oxygen demand as a trigger of daily life ischemia.

Subject Categories:

  • Medicine and Medical Research
  • Anatomy and Physiology

Distribution Statement: