Accession Number:

AD1012339

Title:

Transforming Growth Factor Beta and Ciliary Neurotrophic Factor Synergistically Regulate Vasoactive Intestinal Peptide Through the Cytokine Response Element

Descriptive Note:

Technical Report

Corporate Author:

Uniformed Services University Of The Health Sciences Bethesda United States

Personal Author(s):

Report Date:

2000-09-05

Pagination or Media Count:

87.0

Abstract:

Ciliary Neurotrophic Factor CNTF and Transforming Growth Factor-Beta TGF-Beta are members of two distinct cytokine families that utilize different receptors and signal transduction pathways. Both CNTF and TGF-Beta can induce transcription of the gene encoding the neuropeptide Vasoactive Intestinal Peptide VIP in neuroblastoma cells.

Subject Categories:

  • Medicine and Medical Research
  • Genetic Engineering and Molecular Biology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE