Transforming Growth Factor Beta and Ciliary Neurotrophic Factor Synergistically Regulate Vasoactive Intestinal Peptide Through the Cytokine Response Element
Uniformed Services University Of The Health Sciences Bethesda United States
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Ciliary Neurotrophic Factor CNTF and Transforming Growth Factor-Beta TGF-Beta are members of two distinct cytokine families that utilize different receptors and signal transduction pathways. Both CNTF and TGF-Beta can induce transcription of the gene encoding the neuropeptide Vasoactive Intestinal Peptide VIP in neuroblastoma cells.
- Medicine and Medical Research
- Genetic Engineering and Molecular Biology