Contributions of Early Versus Later-Generated Cortical Layers to the Development of Laminar Patterns in Ferret Somatosensory Cortex
Uniformed Services University Of The Health Sciences Bethesda United States
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The inside-out sequence of generation and formation of the cortical layers is well documented and has been observed in many species. While it is recognized that the early-generated components of cerebral cortex are essential for the formation of important architectural structures, the contributions of later generated cortical layers have not been completely addressed. This study examines the role of individual cortical layers in the development of the cortical laminae by disrupting the formation of specific cortical layers with the antimitotic methylazoxymethanol MAM.