Adherence of Enterohemorrhagic Escherichia coli to Human Epithelial Cells: The Role of Intimin
Uniformed Services University Of The Health Sciences Bethesda United States
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Enterohemorrhagic E.coli EHEC is the leading cause of infectious bloody diarrhea in the United States as well as acute renal failure among U.S. and Canadian children. EHEC colonize the large bowel and produce Shiga-like toxins SLTs that are considered essential for EHEC virulence. EHEC cause intestinal attaching and effacing AE lesions in experimental animals and carry a homologue of the enteropathogenic E. coli EPEC eaeA E. coli attach and efface locus.