Accession Number:

AD1009450

Title:

Investigation of Microcavitation-Induced Effects using in Vitro Models for Traumatic Brain Injury

Descriptive Note:

Technical Report,01 Jan 2013,31 Dec 2015

Corporate Author:

University of Illinois at Chicago Chicago United States

Personal Author(s):

Report Date:

2016-08-25

Pagination or Media Count:

42.0

Abstract:

The project was focused on the development of in vitro biomimetic systems to examine the impact of microcavitation in the brain tissue. We have successfully designed and validated several biosystems to elucidate quantitatively potential biophysical and molecular mechanisms mediating bioeffects which arise from blast-induced shock waves and subsequently generated microbubbles i.e., microcavitation. The coupling mechanisms responsible for the bioeffects of microbubbles in brain tissues can now be better understood with detail, and lead to formulation of strategies to reverse some of the observed adverse effects.

Subject Categories:

Distribution Statement:

APPROVED FOR PUBLIC RELEASE