In-vitro Synthesis of Gold Nanoclusters in Neurons
Technical Report,01 Aug 2013,31 Oct 2014
US Army Research Laboratory Aberdeen Proving Ground United States
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Gold nanoclusters AuNCs synthesized intracellularly have potential for use as in-vivo or in-vitro pressure probes for evaluating the effects of traumatic brain injury. AuNCs were grown within NG-108-15 neuroblastoma-glioma hybrid cells, indicated by increased fluorescence intensity at 488 nm. Effect of gold salt concentration on fluorescence intensity was evaluated. Cell viability at 24-h postgold salt addition was tested via an MTS cell viability assay.