Guided Interventions for Prostate Cancer Using 3D-Transurethral Ultrasound and MRI Fusion
Technical Report,29 Sep 2014,28 Sep 2015
University of California, Los Angeles Los Angeles United States
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Gland-sparing procedures that target specific areas of the prostate have been reported, using laser and HIFU techniques. These focal therapies require real-time visualization of the prostate during intervention, which is cumbersome to perform while the patient is in an MRI. Magnetic Resonance-Ultrasound MR-US fusion allows for specific targeting of the tumors in real-time during clinical interventions,outside of an MR suite. However, existing MR-US fusion exclusively utilizes TRUS. By utilizing a circumferentially wrapped catheter-based transducer, the entireprostate may be visualized at once improving image registration and reducing motion errors. 3D TUUS imaging has been demonstrated in a phantom setting illustrating that the entire prostate gland can be visualized at once. This imaging advance may serve as a platform technology allowing the development of image guided focal prostate therapy.