Accession Number:

AD1008137

Title:

Obesity/Overweight in Persons with Early and Chronic SCI: A Randomized Multi-Center Controlled Lifestyle Intervention

Descriptive Note:

Technical Report,30 Sep 2011,29 Sep 2012

Corporate Author:

University of Miami Miller School of Medicine Miami United States

Personal Author(s):

Report Date:

2012-10-01

Pagination or Media Count:

436.0

Abstract:

The overarching study objective is to reduce health hazards from an overweightobese body habitus and co-morbid cardiometabolic disorders in people with SCI, and to improve their life quality. The study is a four-year multi-center randomized clinical trial RCT conducted at 2 SCI rehabilitation research centers and two Veterans Affairs Medical Centers. The study is modeled after the Diabetes Prevention Program DPP, an NIH-sponsored 27-center RCT that reported a sustained 7 body weight reduction in pre-diabetic individuals accompanied by a 58 decrease in progression to type-2 diabetes. The lifestyle intervention approach incorporating diet, exercise, and behavioral adjustments was more effective than pharmacotherapy, benefited both genders and persons of all races, and has lasted 10 years after initiation.

Subject Categories:

Distribution Statement:

APPROVED FOR PUBLIC RELEASE