Treatment of Early Post-op Wound Infection after Internal Fixation
Technical Report,15 Sep 2014,14 Sep 2015
Vanderbilt University Medical Center Nashville United States
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Severe fractures are common in modern warfare with fractures being fixed via internal fixation of plates and screws to hold the fracture stable while the bone heals. Approximately 10-40 of severe fractures fixed with internal fixation develop a deep wound infection during the healing process. Thus, the overall goals of this study are to 1 evaluate the effect of treatment of post-op wound infection in long bones after fracture fixation or joint fusion and either Group 1 operative debridement and PO antibiotic treatment for 6 weeks or Group 2 operative debridement and IV antibiotics for 6 weeks and 2 build and validate a risk prediction model for failure of treatment of early postoperative wound infections after fixation of fractures or joint fusion.