Analysis of Novel Prostate Cancer Biomarkers and their Predictive Utility in an Active Surveillance Protocol
Technical Report,01 May 2014,30 Apr 2015
Massachusetts General Hospital Boston United States
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The Research Project supported by this DOD PCRP Physician Research Training Award investigates novel biomarkers for prostate cancer detection and the investigation of biomarkers in active surveillance. This report summarizes the research and accomplishments in the fourth year of this award. In this year, I have had continued success in investigating potential proteomic prostate cancer biomarkers. In addition, we have begun to investigate metabolomic signatures in prostate cancer in urine and tissue. I also have continued my clinical investigation of men with prostate cancer on active surveillance. We published a manuscript on our cohort series and have presented at national meetings our updated investigations on young men on active surveillance for low risk prostate cancer.