Accession Number:

AD1006966

Title:

3,3'-Dioctadecyloxacarbocyanine perchlorate (DiO) as a Fluorogenic Probe for Measurement of Critical Micelle Concentration

Descriptive Note:

Journal Article - Open Access

Corporate Author:

University of Utah Salt Lake City United States

Report Date:

2015-07-22

Pagination or Media Count:

9.0

Abstract:

Critical micelle concentration CMC is a key factor in applications of amphiphilic molecules, as it dictates the assembly state of the molecules. Nile Red NR is often used as a fluorogenic dye for the measurement of CMC values, but we have observed that NR is prone to aggregation, which leads to reduced reliability in CMC measurements. Here we evaluate 3,3-dioctadecyloxacarbocyanine perchlorate DiO as an alternative fluorogenic dye for the measurement of CMC values. Both NR and DiO provide values comparable to those reported in the literature. However, we demonstrate that DiO provides improved consistency and is more user friendly than NR for measurement of CMC values.

Subject Categories:

  • Atomic and Molecular Physics and Spectroscopy

Distribution Statement:

APPROVED FOR PUBLIC RELEASE