Risk Stratification of Stress Fractures and Prediction of Return to Duty
Technical Report,15 Nov 2014,14 Nov 2016
MASSACHUSETTS GENERAL HOSPITAL BOSTON BOSTON United States
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This first annual report reviews progress towards completing each of our three study tasks. Major accomplishments include IRB and HRPO approvals for all study protocols, hiring and training of staff at MGH, as well as the initiation of subject recruitment and enrollment. In study Task 1 we aim to determine the sex- and race-ethnicity-specific bone traits that may contribute to stress fracture risk in military recruits. We are ahead of enrollment projections, with 61 of 120 subjects enrolled to date n 40 White women, 14 White men, 6 Black women, 1 Black man. In study Task 2 we aim to quantify changes in bone structure and bone metabolism in recruits before and after Basic Combat Training BCT. Enrollment n161 and data collection are complete, and data analysis is ongoing. Finally, for study Task 3 we aim to characterize recovery and predict bone-healing trajectories and develop return-to-duty guidelines. We hypothesize that changes in bone health during recovery from stress-fracture injury can be quantified and used to develop evidence-based RTD. Enrollment is underway, with 3 women with recent stress fracture enrolled.
- Anatomy and Physiology
- Medicine and Medical Research
- Military Forces and Organizations