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Identifying Immune Drivers of Gulf War Illness Using a Novel Daily Sampling Approach

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Technical Report,30 Sep 2014,29 Sep 2015

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University of Alabama - Birmingham Birmingham United States

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The major aim of this research project is to identify aspects of the immune system that are dysregulated in veterans with Gulf War Illness. A second aim is to determine whether identified immune system dysregulations are similar to those found in men with fibromyalgia. To accomplish those aims at UAB, we are recruiting 29 male veterans diagnosed with Gulf War Illness GWI, as well as 2 healthy veteran controls, and 4 males with FibromyalgiaChronic Fatigue Syndrome FMCFS. Participants will complete 25 consecutive days of blood draws and provide daily reports of symptom severity. Analyses will then be conducted to identify immune system factors that correlate with day-to-day symptom fluctuations in the participants. Ultimately,this information may be used to develop new treatments that specifically target the pathophysiological mechanisms of Gulf War Illness.

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