Accession Number:

AD1004022

Title:

Towards a Molecular Understanding of Noise-Induced Hearing Loss

Descriptive Note:

Technical Report,30 Sep 2014,29 Sep 2015

Corporate Author:

University of Maryland Baltimore United States

Personal Author(s):

• Hertzano,Ronna

Report Date:

2015-10-01

Pagination or Media Count:

21.0

Abstract:

The purpose of this project is to understand the inner ear cell type-specific changes induced by different types of noise and pre-conditioning interventions. To date, we have calibrated the noise exposures, and successfully completed tissue collection and processing for RNA-seq of baseline and noise treated samples at two different time points following noise exposure. We also established the sequencing conditions for all libraries and have been critically comparing the pre-conditioning treatments to carefully select the ones for further investigation.

Descriptors:

• EAR
• senses(physiology)
• auditory defects
• noise
• exposure(physiology)
• therapy
• gene expression

Subject Categories:

Distribution Statement:

APPROVED FOR PUBLIC RELEASE