A Randomized Placebo-Controlled Trial of D-Cycloserine for the Enhancement of Social Skills Training in Pervasive Development Disorders
Technical Report,01 Mar 2014,28 Feb 2015
Indiana University Health Indianapolis United States
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The main objective of this application is to determine whether D-cycloserine DCS can enhance the efficacy of social skills training SST in the treatment of children and young adolescents with autism spectrum disorders ASDs. We will evaluate the efficacy, tolerability, and last effects of DCS given one hour prior to each of 10 weekly SST sessions for the treatment of social impairment in 68 children and young adolescents ages 5-11 years with ASDs during a randomized placebo-controlled trial. The safety and tolerability of DCS and durability of treatment response will also be examined.