Accession Number:

AD0900338

Title:

On the Polarography of Methaqualone, Dormutil and Ethinazone, Aolan 5th Report. Polarography of Heterocycles (Zur Polarographie von Methaqualone, Dormutil und von Aethinazon, Aolan 5. Mitt. Polarographie von Heterocyclen),

Descriptive Note:

Corporate Author:

ROYAL AIRCRAFT ESTABLISHMENT FARNBOROUGH (UNITED KINGDOM)

Personal Author(s):

• Pflegel, P.
• Wagner, G.

Report Date:

1971-10-01

Pagination or Media Count:

19.0

Abstract:

2-METHYL-3-2-METHYLPHENYL-3,4-DIHYDROQUINAZOLINONE-4 METHAQUALONE, Dormutil and 2-methyl-3-2-ethylphenyl-3,4-dihydroquinazolinone-4 ethinazone, aolan were reduced at a dropping mercury electrode between pH 0 and 8, with the capture of two electrons per molecule. In the range of concentrations to 0.001 m the reduction leads mainly to the corresponding 1,2,3,4-tetrahydroquinazolinones-4, and in addition the dimers of these compounds, attached at the N1N1 positions, occur at higher concentrations. The mechanism of the electrode reaction is discussed. The possibilities of quantitatively determining the compounds were investigated. Author

Descriptors:

• *HETEROCYCLIC COMPOUNDS
• *HYPNOTICS AND SEDATIVES
• POLAROGRAPHIC ANALYSIS
• BENZENE
• PH FACTOR
• ELECTRODES
• CRYSTALLIZATION
• SOLUBILITY
• SOLUTIONS(MIXTURES)
• MOLECULAR WEIGHT
• ELECTROLYSIS
• CATALYSTS
• THIN LAYER CHROMATOGRAPHY
• UNITED KINGDOM

Subject Categories:

• Pharmacology
• Atomic and Molecular Physics and Spectroscopy

Distribution Statement:

APPROVED FOR PUBLIC RELEASE