Nosematosis in Laboratory Animals
FORT DETRICK FREDERICK MD
Pagination or Media Count:
A review of the literature and personal observations on nosematosis of laboratory rodents are presented. The disease, caused by the protozoan Nosema cuniculi, is a spontaneous enzootic entity of laboratory rodents. The presence of occult infections in laboratory animals has confounded the results of numerous experiments. The importance of diagnosing nosematosis in laboratory animals, therefore, cannot be overemphasized. Clinical signs are usually absent, and infection can be recognized only by necropsy or by recovery of the organism following intraperitoneal inoculation of infected material into mice. Gross and histopathological lesions are described for various laboratory animals. The mode of natural transmission of the disease has not been determined. There is a need for further research on transmission and control of nosematosis as well as vitro culture of the organism.
- Animal Husbandry and Veterinary Medicine