Accession Number:

AD0860651

Title:

Studies on Microbial Degradation of Toxic Phosphorus Esters. Part 1. Detoxification of O,O-Dimethyl-O-(2-carbomethoxy-1-methylvinyl) Phosphate by Soil Bacteria.

Descriptive Note:

Interim rept.,

Corporate Author:

AIR FORCE ARMAMENT LAB EGLIN AFB FL

Personal Author(s):

Report Date:

1969-09-01

Pagination or Media Count:

19.0

Abstract:

In an attempt to find a new method for detoxifying cholinesterase-inhibiting, organophosphorus compounds, studies were undertaken to isolate bacteria capable of degrading O,O-dimethyl-O-2-carbomethoxy-1-methylvinyl phosphate Phosdrin. Degradation of the insecticide was determined by gas chromatography, while decreased toxicity was confirmed by measuring cholinesterase activity with a recording pH stat. Of the thirty cultures screened, two showed 80-90 degradation of the original 20 ppm Phosdrin in 10 days, with a corresponding decrease in toxicity. One of the cultures was isolated from soil collected on Eglin Air Force Base, Florida, and the other as a laboratory contaminant. The bacteria were identified as two different strains of Bacillus megaterium. Author

Subject Categories:

  • Toxicology
  • Biochemistry

Distribution Statement:

APPROVED FOR PUBLIC RELEASE