Accession Number:

AD0860413

Title:

Controlled Oxidation-Reduction Potential in Submerged Tissue Culture Fermentation in Pilot-Scale Fermentors,

Descriptive Note:

Corporate Author:

FORT DETRICK FREDERICK MD

Personal Author(s):

Report Date:

1969-09-01

Pagination or Media Count:

32.0

Abstract:

Operations of a submerged tissue culture pilot facility are presented. Oxidation-reduction potential ORP was controlled, and its effects on fermentation are discussed. A strain of Earles L cells was grown to as high as 4400000 viable cells per ml. Cultures were grown without the aid of antibiotics. An internal standard was developed to calibrate the redox measuring system. Author

Subject Categories:

  • Microbiology
  • Industrial Chemistry and Chemical Processing

Distribution Statement:

APPROVED FOR PUBLIC RELEASE