Accession Number:

AD0854130

Title:

Nitrosoguanidine Mutagenesis and Chromosomal Replication in Staphylococcus Aureus

Descriptive Note:

Corporate Author:

FORT DETRICK FREDERICK MD

Personal Author(s):

Report Date:

1969-05-01

Pagination or Media Count:

9.0

Abstract:

The number of mutations induced by nitrosoguanidine per 1,000,000 survivors is the same for exponential cells as for cells with resting, complete chromosomes. During synchronous chromosomal replication, no peak of mutations per million survivors appears at the time of duplication of the genes examined. It was concluded that for Staphylococcus aureus the replicating region of the chromosome is no more susceptible to nitrosoguanidine mutation than is the resting chromosome.

Subject Categories:

  • Microbiology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE