Foot and Mouth Disease Vaccine Prepared from Virus Cultivated in Calf Kidney Cell Suspension
ARMY FOREIGN SCIENCE AND TECHNOLOGY CENTER CHARLOTTESVILLE VA
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Five series of foot and mouth disease vaccine were prepared in calf kidney cell suspensions. Three were highly active, protecting all vaccinated cattle from controlled infection. One series was satisfactory, protecting three out of four animals, with no evidence of generalized disease. One series was less effective, with one example of generalized disease. Culturing in calf kidney cell suspensions allows one to obtain large quantities of foot and mouth disease virus more easily than the monolayer culture method.