Non-specific Resistance. Bacterial Interference and Implantation (Resistance Non Specifique. Interference et Implantation Bacterienne)
ARMY BIOLOGICAL LABS FREDERICK MD
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For many years, the existence of nonspecific resistance had been known which was independent of the specific resistance factors against infectious agents composed partly of humoral factors antibodies, partly on tissue factors, and especially on delayed hypersensitivity. The mechanism of the nonspecific resistance is discussed. It was found to be dependent on temperature, on the endocrine and nutritional state of the recipient, and occasionally on genetic factors. Certain species of mice are resistant to certain salmonellae as well as to Saint Louis encephalitis. Certain aspects of the mechanisms involved can be understood from the results obtained by the study of viral interference of the stimulation of the reticuloendothelial system and bacterial interference. The experimental results obtained thus far have already permitted the proposal of new methods of human therapeutics.
- Medicine and Medical Research