Toxicity of O-Chlorobenzylidene Malononitrile (CS) in Trioctylphosphate (TOF) Solutions
Technical rept. Jan-Dec 1968
EDGEWOOD ARSENAL ABERDEEN PROVING GROUND MD
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As solutions containing 1 o-chlorobenzylidene malononitrile CS in trioctylphosphate TOF have been proposed for use in riot control situations, a series of toxicological tests was conducted in animals. Results showed that the doses tested are not permanently injurious to the eyes. Effects on skin ranged from none to necrosis, and the affected ares usually healed within 2 weeks. When the mixtures were directly injected into the trachea, some evidence of congestion and pneumonia was seen. But the severity and duration of signs were not in a category that would warrant veterinary treatment under conditions of normal animal care. The reported studies indicate that no irreversible damage is expected with 1 CSTOF solutions as long as the dose ranges shown to be safe in this paper are not exceeded.
- Chemical, Biological and Radiological Warfare