Pesticinogeny, an Identifying Characteristic of Pasteurella Pestis
FORT DETRICK FREDERICK MD
Pagination or Media Count:
Current methods of identifying Pasteurella pestis rely heavily on tests specific for detecting fraction I, the envelope antigen. Pesticin I, a bacteriocin inhibitory for Pasteurella pseudotuberculosis, has been demonstrated in nearly all strains isolated from human infections. The results of use of this characteristic as an identifying trait for P. pestis were compared with results reported for detecting fraction I by fluorescent antibody and antiserum agar techniques. Data indicate that although certain atypical strains of P. pestis fail to react in one system or the other, a combination of these tests provides positive identification in all cases. The rapidity, simplicity, and specificity of this test makes it a valuable tool in the study of plague infections and an important adjunct to methods currently in use.
- Medicine and Medical Research