Accession Number:

AD0848641

Title:

Development in Vitro of 'Half Eggs' and Single Blastomeres Isolated from Two-, Four-, and Eight-Cell Mouse Ova

Descriptive Note:

Corporate Author:

FORT DETRICK FREDERICK MD

Personal Author(s):

Report Date:

1968-12-01

Pagination or Media Count:

19.0

Abstract:

The extent of mouse blastomere lability was studied by isolating and growing in vitro blastomeres as various components of two-, four-, and eight- cell ova. The results were in accord with the view that blastomeres of the eight-cell ovum and possibly even later stages have the capability of becoming either trophoblast or inner cell mass, depending on location in the cell aggregate at the time of blastulation. The formation of trophoblastic vesicles from single blastomeres of four- and eight-cell ova is a result of an inadequate number of cells at time of cavitation.

Subject Categories:

  • Anatomy and Physiology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE