IMMUNIZATION OF WHITE MICE TO ECTROMELIA WITH VACCINE VIRUS - II
ARMY BIOLOGICAL LABS FREDERICK MD
Pagination or Media Count:
Intrapertioneal booster inoculation of vaccine virus strain Ankara renews immunization to induced intraperitoneal ectromelia infection. The protection of the booster shot becomes attenuated during the same interval of time as that of the initial vaccination, i.e. 12 to 26 weeks. Intraperitoneal administration of appropriate doses of commercially available vaccine lymph and or tissue-culture vaccine produces the same immunization to induced intraperitoneal ectromelia infection as the inoculum from vaccine strain Ankara infected chorio-allantois membranes. Intraperitoneal vaccination increases the survival rate of a stock of mice with latent ectromelia as against non-vaccinated controls of the same stock. Female mice develop a higher immunity than male animals.
- Anatomy and Physiology