CHEMICAL BINDING OF PROTECTIVE AGENTS TO THE HUMAN STRATUM CORNEUM
Technical Report,01 Jul 1965,01 Jul 1968
HARVARD MEDICAL SCHOOL BOSTON MA BOSTON United States
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Report covers laboratory study and clinical trials on a series of chemical formulations to find means of chemically binding agents to skin elements or of permanent absorption to provide long term 7 days protection from sunburn regardless of heavy sweating or washing actions. Results are reported in detail and tabulated. Two preparations were developed which were effective for long term exposure 4 hr after single application and were resistant to washing action. Preparations did not interfere with tanning action and were cosmetically acceptable. Two were very effective under conditions of bright sun in dry climate or high elevation and snow environments. Stable binding to skin providing 7-day or longer protection was not achieved.