DID YOU KNOW? DTIC has over 3.5 million final reports on DoD funded research, development, test, and evaluation activities available to our registered users. Click HERE
to register or log in.
ANTIMICROBIAN ACTIVITY OF CHLORPROMAZINE, ANTAGONISTIC ACTION OF ADENOSINE-5 TRIPHOSPHATE (ATP) AND SOME ELECTRONIC ASPECTS OF THOSE ACTIONS
ARMY BIOLOGICAL LABS FREDERICK MD
Pagination or Media Count:
A study was made of the antimicrobian activity of chlorpromazine, which theoretical chemistry calculations represent as a strong donor of electrons. The antagonistic action of adenosine-5 tiphosphate ATP was also shown. Its addition to a culture of staphylococci which had been arrested by chlorpromazyne makes possible the renewal of growth. The lyse of the same germ by an appropriate phage, decelerated by chlorpromazine, was accelerated by a simultaneous addition of biliverdin, a substance presenting the properties of a good acceptor of electrons.
APPROVED FOR PUBLIC RELEASE