SOLUBLE TOXINS OF SOME ENTEROBACTERIACEAE
ARMY FOREIGN SCIENCE AND TECHNOLOGY CENTER CHARLOTTESVILLE VA
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Various representatives of the Family Enterobacteriaceae, including the genera Salmonella, Shigella, Esherichiae, produce soluble toxic substances during their life. These toxins are able to produce various damages, even death, in the experimental animals, depending upon the amount of administered dose. Experiments on rabbits and white mice proved that the toxins are thermostable, and they have antigenic and immunogenic properties, but they are not suitable for toxoid preparation. They have a neurotoxic, paralytic effect upon motor cells of the anterior horn in the spinal cord.