Accession Number:

AD0838940

Title:

STUDY OF BRUCELLA POLYSACCHARID ANTIGENES. II. IMMUNOLOGICAL BEHAVIOR

Descriptive Note:

Corporate Author:

ARMY BIOLOGICAL LABS FREDERICK MD

Personal Author(s):

• Serpa, C. E.
• Fuks, M. A.

Report Date:

1965-04-26

Pagination or Media Count:

8.0

Abstract:

In this investigation, observations were carried out on the immunological behavior in vivo and in vitro of the polysaccharidic fraction isolated by the Fuller technique, starting with Br. abortus B99. It was found that the fraction being investigated was a complex hapten, atoxic to rabbits and sorologically active in precipitation tests. In animals that had been previously innoculated with Brucella, the injection of the polysaccharidic antigen did not induce reactions of allergic nature, although it did give a passive cutaneous anaphylaxis test. At the same time, its innoculation did not produce any change of temperature, weight, leucocytic formula, or electrophoretic profile of the sera of the animals.

Descriptors:

• *BRUCELLA
• POLYSACCHARIDES
• IN VITRO ANALYSIS
• ANTIBODIES
• TRANSLATIONS
• IMMUNE SERUMS
• CHEMICAL PRECIPITATION
• IMMUNITY
• IN VIVO ANALYSIS
• BOVINES
• ANTIGENS
• ELECTROPHORESIS
• BRAZIL
• SERODIAGNOSIS
• INJECTIONS(MEDICINE)
• ALLERGIC DISEASES

Subject Categories:

• Medicine and Medical Research
• Microbiology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE