Accession Number:

AD0838561

Title:

RED CELL RECEPTORS FOR ARBORVIRUSES: THE CELL LIPIDS

Descriptive Note:

Corporate Author:

ARMY BIOLOGICAL LABS FREDERICK MD

Personal Author(s):

• Nicoli, J.

Report Date:

1965-12-01

Pagination or Media Count:

22.0

Abstract:

A study of the behavior of red cells subjected to various chemical or enzymatic treatments demonstrates the presence of lipids in the cell site receptor of arborviruses. Inhibiting lipids are present in red cells, either agglutinable or non-agglutinable by arborviruses. The responsible fractions seem to be phosphatidylcholines. They are the same for all the viruses studied. The pH conditions for inhibition are analogous to those of hemagglutination. These facts suggest certain hypotheses on the actual nature of the red cell receptor site, and of the bonds between this site and the virions.

Descriptors:

• *LIPIDS
• *ERYTHROCYTES
• *ARBOVIRUSES
• FRANCE
• SEPARATION
• TRANSLATIONS
• INHIBITION
• PH FACTOR
• CELL STRUCTURE
• CHROMATOGRAPHIC ANALYSIS
• CYTOCHEMISTRY
• AGGLUTININS

Subject Categories:

• Biochemistry
• Microbiology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE